Kratom
Drug Facts
What
is Kratom?
Kratom (Mitragyna
speciosa) is a tropical evergreen plant aboriginal to the Southeast Asia.
Its leaves are devoured by drying, smoking, chewing and putting into the Kratom capsules.
Leaves of the Kratom have long been used by the people of that region to
alleviate pain and turn away the fatigue. Prozialeck et al, an article
published in 2012, showed evidence that the Kratom had been used for the
self-supervision of the pain relief and opioid withdrawal in the US. Because
the constituents of chemical present in the Kratom have pharmacologic
functions, Kratom was classified as the the herbal product by Drug Enforcement
Administration of the United States.
Other Names For Kratom
Kratom can also be called as Biak,
Ithang, Ketum, Thom, Herbal speed ball, Ketum and Kakuam.
How You Can Consume Kratom?
You can consume it by the following
methods:
· Put in a capsule
· Take as a pill
· Stew the powdered leaves
· Chew the leaves of Kratom
· Brew its leaves as a tea
· You can also consume it in food
Drug Enforcement Administration (DEA) Kratom Scheduling
Kratom has been a controversial drug on
the DEA’s list of drugs for several years. DEA planned to place Kratom in Schedule I on August 31, 2016 and
impose ban on it. A number of the Kratom admirers cast aspersions on it and
contested for its legality. American Kratom
Association supported its use and thus laws were enforced in the approval of
Kratom production and uses. Still there are some cities in the United States
where Kratom is still banned.
Kratom Pharmacology
Food and Drug
Administration (FDA) reported in February 2018
that Kratom contains opioid properties. Alkaloids, which are responsible to
alleviate pain, have been identified in the Kratom with substantial chemical
properties. These alkaloids attach to the opioid receptors of the brain and
helps in minimizing the stress or depression level. It also results in peaceful
sleep without cramps of muscles.
Action of the primary mitragynine takes
place at the mu and delta opioid
receptors. According to the findings of Animal studies, the action may take
place at the spinal cord pathways of serotonergic and noradrenergic. The
impacts of the receptors of opioid are fluctuating with opioid antagonist
naloxone. Mitragynine is the psychoactive compound of M. speciosa Korth and manages the opioid-like effects. It is 13 times
more intoxicating than morphine. The 7-hydroxymitragynine has a greater attraction for the
receptors of opioid.
Kratom Effects on the Brain
A number of researches have proved
Kratom as a harm reduction drug, most primarily when it substitutes for the
opioids among the addicts. The leaves of the Kratom has two main compounds,
mitragynine and 7-hydroxymitragynine. These compounds interrelate with the
receptors of opioid in brain that results in decreased pain and produce
sensation. Kratom can affect brain in the same way as stimulants. Mitragynine
interacts with the brain receptors system that provides stimulant effects.
Kratom jacks up the mood and lessens stress. Kratom strain enhances the memory power and strengthens brain activities. These
strains help in cognitive improvements as well.
Kratom Effects on the Health
Kratom has such components that have the
capability to control insulin growth and thus it has proved as a treatment for
Diabetes. Alkaloids in the Kratom reduce anxiety and help to sustain a peaceful
sleep [1]
On the other hand, the excessive use of
Kratom results in sedation and the increased urinary outflow. Its low dose
leads to the active alertness and enhances physical energy. Kratom addictive
may suffer hallucination and delusion. They show
perplexity in their attitude. Nausea, sweating, increased urination,
constipation and loss of appetite are caused by Kratom addiction. Its long term
intake results in anorexia, constipation and insomnia.
Can Kratom Cause Addiction?
As Kratom is obtained from the natural
plants, it should not make to think that it cannot be addictive. There are many
other drugs that are consumed from plant but are addictive such as cocaine,
obtained from coca leaves. Similarly, nicotine is consumed from tobacco plant
and heroin from opium poppy. Kratom is found to be addictive after its use by
the Southeast Asian countries because of its following typical characters:
· Narcotic withdrawal
· The attitude of drug-seeking
· Tolerance
· Cravings
· Feeling of escaping the negative emotions
· Haunting thinking about using the drug
· Enduring a temporary space from the stresses of life.
Can You Overdose Kratom?
According to the National Institute on Drug Abuse, overdose on Kratom may lead to the potentially harmful impacts
that include the cardiac arrest, high blood pressure and extreme dizziness. Most of the Kratom
addicts are found with the severe seizures that hamper the neurological activities
of brain and can cause death eventually.
Is Kratom Safe?
No doubt it is one of the most searched
questions about
the Kratom. The Food and Drug
Administration (FDA) reported that there are no approved uses of the Kratom by
FDA but still there are particular apprehensions on it. In order to find out
the main fact either if it is safe or has some medical sort of practicality.
The research center in the United States has manipulated almost 45 deaths of
the Kratom addicts, although majority of them were consuming other drugs along
with the Kratom or taking the products that were blighted with the toxic
bacteria such as salmonella. An agency has annihilated all the
companies and industries that used to sell Kratom for the purpose of pain
relief.
How Can You Detect Kratom in Your Body?
Mitragynine which is the main component
of the Kratom has a half-life of 24 hours almost. In the body, It can be
identified by the technical lab testings.
Ø Urine
Urine can identify the use of Kratom for almost up to a week.
Ø Breast Milk
The psychoactive ingredients of
Kratom are thought to present in the milk of
the breast. Thus, it can be used for the identification process.
Ø Hair
Researches have shown that hair can also use for the detection of
Kratom intake but this test is not available yet.
Ø Blood
For a number of days of Kratom intake, blood is used for its
detection procedure.
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